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Application of Cryogenic Engineering in Medical Industry

Mar 07, 2025

Modern medicine’s need for extreme low temperatures makes cryogenic engineering essential. Fullcryo provides specialized cryogenic solutions to advance its use in healthcare.

1. What is cryogenic engineering?

Research and application in many fields are inseparable from extremely low temperature conditions. The role of cryogenic engineering is to use relevant cryogenic technology or cryogenic equipment for different application scenarios to generate, maintain and control the cryogenic environment.

Cryogenic engineering is a set of technical solutions specially designed to achieve and maintain extremely low temperatures. This complex engineering system consists of multiple core parts, including cryogenic refrigeration equipment, cryogenic storage and transportation equipment, temperature control and measurement engineering, etc.

2. Core equipment of cryogenic engineering

The construction of cryogenic engineering is inseparable from cryogenic equipment. Fullcryo provides the most professional and comprehensive cryogenic equipment.

Cryogenic refrigeration equipment is the heart of cryogenic engineering, and refrigerators are usually responsible for generating cold. Backed by the support of China’s cutting-edge scientific team, Fullcryo independently develops a series of large-scale cryogenic refrigeration equipment, mainly including helium refrigerators (2-20K) and helium liquefiers. Helium refrigerators reduce the temperature through a series of compression, condensation, and expansion steps to directly provide a cryogenic environment. Helium liquefiers produce liquid helium, a cooling medium, by converting helium gas into liquid helium.

Cryogenic storage and transportation equipment is designed to safely store and transport cryogenic fluids. Fullcryo provides equipment such as dewar flasks, cryogenic liquid storage tanks, and cryogenic transportation pipelines. Because dewar flasks are easy to transport, they are suitable for small-scale laboratories and medical fields such as liquid helium and liquid nitrogen. Cryogenic liquid storage tanks are an industrial-grade storage system that transports products by liquefying gases. They are widely used in aerospace propellants (liquid hydrogen/liquid oxygen) and LNG natural gas storage, and are suitable for customers with large gas consumption. Cryogenic transportation pipelines are used for long-distance transportation of cryogenic fluids. They are usually installed and built on-site by the technical team. Customized solutions can be selected for different customers.

3. Key applications in the medical industry

The application of cryogenic engineering technology in the medical field can be traced back to the mid-20th century. The early application of cryogenic anesthesia technology in clinical practice marked the medical practice of cryogenic technology, but MRI is a typical commercial application of cryogenic engineering technology, which kicked off. Cryogenic engineering is currently widely used. From basic scientific research to clinical practice, from disease diagnosis to treatment methods, they are inseparable from the support of this key technology. Especially in the modern medical field, many high-end technologies are inseparable from extremely low temperature environments.

(1) Superconducting cooling of MRI

When we go to the hospital for medical examinations, those professional equipment also use cryogenic engineering. The most typical example is that MRI (magnetic resonance imaging) technology relies on superconducting magnets to generate high-resolution images, and these superconducting magnets can only work stably below -269℃ (4.2K). However, helium resources are scarce and expensive, and long-term use will increase the operational burden. Fullcryo’s helium refrigerator uses a closed-loop cooling system, which can greatly reduce the consumption of liquid helium and ensure that MRI equipment operates more stably and economically. Fullcryo’s 4.5K helium refrigerator continues to break through technical barriers, compressing helium gas at high pressure to liquid helium to provide cooling, reducing the consumption of liquid helium and reducing the maintenance requirements of the cooling system. It has been applied in many scientific and medical fields.

(2) Applications in cancer treatment

Cancer treatment technology is constantly progressing to help more and more patients out of the haze of the disease, among which cryoengineering plays a key role, especially in the field of proton therapy and cryoablation. The principle of proton therapy is to precisely control the proton beam through superconducting magnets, directly attacking cancer cells, while reducing the damage to surrounding healthy tissues, thereby improving the precision of treatment. Cryoablation uses extremely low temperature (below -160℃) to directly “freeze” cancer cells, which avoids the trauma caused by traditional surgery and accelerates the recovery of patients. It is believed that in the near future, cryogenic equipment will contribute more to the field of cancer treatment, continuously improve the accuracy of treatment, and improve the treatment experience of patients.

(3) low temperature storage in the biomedicine

In addition to medical imaging and cancer therapy, cryogenic storage is also critical in the biomedical field. For example, mRNA vaccines need to be kept below -70°C or their effectiveness will be reduced; Biological samples, such as stem cells, immune cells, and embryos, require long-term storage in liquid nitrogen (-196°C) to maintain viability. Cryogenic storage equipment in cryogenic engineering can provide accurate temperature control for cell banks, vaccine cold chain and biological laboratories, so as to ensure that vaccines and biological samples can be stored at appropriate temperatures for a long time and help life science research and precision medicine.

(4) Hypothermia in organ transplantation

In organ transplantation, organs need to be transplanted into the recipient as soon as possible after being removed from the donor. The key to the success of the operation is the transportation and preservation of the organs. Specific cryopreservation conditions can improve the activity of organs and reduce cell damage. Cryogenic engineering technology provides precise temperature control technology to ensure that the structure of organs is not damaged during freezing and resuscitation, thereby increasing the chance of successful transplantation. For example, vital organs such as heart and liver usually need to be preserved in an environment of about 4 ° C, and the transfer time from donor to recipient should be shortened as much as possible. Advanced cryopreservation technology is exploring how to better protect cells from cryodamage and provide the possibility to achieve long-term organ preservation in the future.

4.Seeking professional cryogenic engineering solution

In addition to the medical industry, cryogenic engineering is also contributing to other emerging industries, such as in the field of cutting-edge science and space exploration. Fullcryo constantly innovates, actively expands global cooperation territory, and is committed to being at the forefront of global cryogenic projects. Our cryogenic equipment is exported to many countries at home and abroad, and is widely used in large-scale particle collision experiments, deep space exploration missions, superconducting energy research and other advanced projects. Backed by China’s top scientific research team and with professional cryogenic technology, Fullcryo focuses on creating efficient and stable cryogenic systems tailored for customers.

At the same time, Fullcryo’s solutions cover project layout planning, cryogenic system design, cryogenic engineering supporting equipment manufacturing and transportation, cryogenic system commissioning, post-project maintenance and maintenance. Our commitment to making individual adjustments according to the needs of different projects has enabled Fullcryo to participate more widely in the cryogenic infrastructure business in many countries around the world.

 

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